Abstract: Anterior megalophthalmos (AM), also called X\|linked megalocornea, is an rare congenital hypoplasia of ocular anterior segment. 90% of patients was approximately constituted by men. It is characterized by premature cataract and 360° zonular weakness with lens subluxation with megalocorneal, deep anterior chamber and the enlarged sulcus. Recently, cataract surgeries in AM patients still are a debatable point which is prone to challenge mainly because of zonular weakness and capsular bag. Characters of AM and cataract surgeries in AM patients remains unreviewed yet. For cataract and lens dislocation surgery in patients with AM, the proper choice of intraocular lens (IOL) and operation mode are the key points. It is difficult to implement phacoemulsification safely because of the large and unstable capsular bag and zonular weakness. Iris-claw IOL implantation or scleral fixated IOL implantation may be more suitable surgical way for AM patients. It is worthy of further research and exploration that how to choose individualized surgery according to different characteristics of capsular bag in AM patients in order to obtain better surgical effect.

Key words: anterior megalophthalmos, lens subluxation, intraocular lens